Duromine is one of the most popular oral weight-loss drugs in the United states. It does not work on body fat,but actually affects the body by altering the mind. The drug suppresses appetite and helps users transform into healthier eating patterns. It stimulates the brain neuron group to release a series of neurotransmitters called catecholamines, including dopamine, epinephrine, and norepinephrine. These neurotransmitters are signals of action and survival in the brain, related to eating. It also increases brain leptin levels, telling the brain that the stomach is full. It is a drug that helps fight obesity and weight problems and has been recommended by the US Food and drug administration. Prior to the use of duromine, it is clear that any chemical has beneficial effects as well as side effects. The efficacy of duromine depends on the dose, age, sex, physical and mental status of the users. It can increase heart rate and blood pressure, and anyone who has a heart attack should not use it.