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Clomid and Nolvadex are one of the two major SERM (selective estrogen receptor
modulators), which are used to promote testosterone recovery after anabolic
steroid cycle.
To understand how clomid helps this process, let's look at how natural
testosterone production is regulated.
Testosterone production is regulated by a feedback loop that senses not only
testosterone or other androgen levels, but also estrogen levels. This feedback
loop includes the hypothalamus, pituitary, and testes (commonly referred to as
HPTA, or hypothalamic pituitary testicular axis)
When the hypothalamus senses low estrogen levels but not high androgen levels,
it is stimulated to produce more LHRH to signal the pituitary gland, which means
LH releasing hormone. On receiving this signal, the pituitary gland produces
more LH (luteinizing hormone), which in turn signals the testes to produce more
testosterone.
In the anabolic cycle of steroids, high levels of androgen completely stop the
process. If it's just a relatively short period, such as eight weeks, it's not a
real problem. However, over a long period of time, the testes may atrophy. This
can be avoided by using hCG. However, it cannot be avoided that the response of
hypothalamus and pituitary not only depends on the hormone level they feel at a
certain time, but also their response is affected by recent exposure. When
exposed to anabolic steroids for a long time, even if the use of anabolic
steroids is stopped, the reactivity is usually poor.
Clomid, like Nolvadex, works by occupying the binding sites of estrogen
receptors in cells without activating the receptors. This reduces the extent to
which estradiol activates these receptors. In the case of the hypothalamus, this
leads the hypothalamus to "draw" the conclusion that estrogen levels are low. If
androgen levels do not rise, just as they should not after the anabolic steroid
cycle, the hypothalamus is stimulated to produce LHRH. This will help improve
luteinizing hormone and restart production of natural testosterone.
The dosage of clomid is usually 50 mg / day. However, it is worth noting that
clomiphene has a long half-life. Related to this, when taking one dose a day,
the body not only contains the dose, but also accumulates a dose equivalent to
the previous dose for 5 days. It's good: it produces the right blood levels. The
problem is the first use. If you just take 50 mg / day from the beginning, there
won't be such accumulation, and the content will be very low.
For this reason, take 300 mg on the first day, take 100 mg in three times, or
take 50 mg six doses. This will immediately reach the level they should be. A
dose of 50 mg / day will maintain this level.
After day 1, doses above 50 mg are not required and are not recommended. They do
not improve results, but may increase side effects.
Side effects of clomid include increased emotional or visual impairment. In case
of visual impairment, clomipide should be stopped immediately.
Clomid rarely causes libido problems, which may be the problem with Nolvadex.
For this reason, some people prefer it to Nolvadex. Others, who don't have
problems with novadex, may prefer this drug. These two methods can effectively
restore the natural secretion of testosterone. I have a slightly better view of
the effectiveness of clomid, but if one doesn't like the emotional effects of
clomid, or prefers Nolvadex for any reason, Nolvadex is a perfectly acceptable
alternative.
Clomid differs from Nolvadex in that SERMs are usually anti estrogen in some
tissues and estrogen in others. Fortunately, clomid and Nolvadex are both anti
estrogen in the hypothalamus, which makes them very useful in post cycle therapy
(PCT) and have anti estrogen effects in breast tissue, so they can be used as
anti gynecologic drugs. However, clomid is an estrogen in the pituitary gland,
and in some cases can even increase the value of PCT. It may produce estrogen on
at least some of the other neurons in the brain, leading to increased mood.
Clomipide and novad have no other adverse estrogenic effects on body fat and
muscle, or any observed physical properties, but are useful anti estrogen
agents.
After the androgen level dropped to normal level, PCT was treated with
chloramine until the natural testosterone level was completely restored.
To be correct, clomid is a brand name: clomiphene citrate products are usually
used, but they are often referred to as clomid. Clomiphene citrate is a widely
available drug, and even more widely as a research chemical, often oral in
liquid form.
This product was added to our catalog on Saturday 01 August, 2020.