T3 Triiodothyronine Profile

T3 (triiodothyroxine, liothyronine, Cytomel) is a thyroid hormone drug widely used for fat loss, especially in the context of the anabolic steroid cycle. T3 is the result of T4 (thyroxine) produced by the thyroid gland, which is naturally produced in the human body. Oral administration of T3 can produce higher serum T3 levels than in natural conditions, resulting in faster fat loss and, in some cases, greater growth hormone production and greater anabolism.


Instability of T3
Regarding the dosage of T3, the first thing to consider is that the drug itself is not stable, even some tablet drugs will lose efficacy over time. Liquid preparations are more likely to lose their potency. The doses given below refer to fully effective T3, e.g. U.S. - made or European drugs still in validity. In many cases, the T3 content of other T3 products will be lower or even far lower than the label indicates.

For this reason, I suggest looking for authentic T3 drugs, preferably from the United States or Europe. Otherwise, the dose may be uncertain or deceptive. For example, when using an inefficient product, one may find that "150 micrograms" per day is an appropriate dose, but when using a full potency product, it is an extremely excessive dose.


T3 dosage
I recommend two ways of administration.
In the first approach, the goal is to achieve a sustained advantage in weight loss, or to help maintain near personal ideal body composition. In this method, the T3 dose is very low, preferably 12.5 mcg / day, but in some cases as high as 25 mcg / day. At the low end of this range, a typical thyroid test will not show detectable inhibition even if used for a long time. At the high end, moderate inhibition can sometimes be seen, but the effect is better than that without T3, and the inhibition is rapidly reversed after T3 is stopped.
In the second method, the goal is to achieve a significant increase in fat loss at the known cost of induced thyroid suppression. The most preferred dose is about 50 mcg / day, but in some cases up to 75 mcg / day. This use is best not to last, but only for a limited period of time, such as 8-12 weeks, although there is no exact time requirement.


Dividing dose of T3
Because of the short half-life of T3, in addition to the small daily total dose, it is better to give a single dose of T3. For example, a dose of 12.5mcg. D, preferably once in the morning, but 50 micrograms per day is better than taking the full dose in three to four times a day.
Post-cycle suppression of natural thyroid production
After long-term use of T3 at inhibitory dose, natural products will be inhibited for a period of time after T3 is stopped. Generally speaking, the duration is related to the use time. In the case of short-term use, there is usually no obvious post functional cycle, but with the extended cycle, the duration of low function can be as long as 6 weeks in some cases.

The article "recovery of pituitary thyrotropism after cessation of long-term thyroid suppression therapy" provides an example of the difficulties that may be encountered in the recovery of good thyroid production after long-term oral administration of thyroid gland.

Although in this study, all subjects returned to "normal" thyroid production, as is often the case in bodybuilding, the "normal" they eventually got was the bottom end of the normal range, about 40 UG / dl of total serum T4 and about 80 μ g / dl of total serum T3. These are not the levels that people want to reach, and they are so low that their metabolism is impaired.


Effects of T3 overdose
High doses of T3, usually starting at about 75 μ g / day, but in some cases until about 100 μ g / day, can cause tachycardia (increased heart rate) and muscle weakness, and may catabolize or at least reduce anabolism. Of course, high doses of anabolic steroids can mask the latter.
High levels of T3 are dangerous for the heart.
Interaction between high serum T3 and IGF-1
High level of T3 will reduce the level of IGF-1, which will reduce the efficiency of GH anabolism, but will not change the weight loss effect of GH.
This effect makes some people think that T3 can reduce the side effects of GH; in fact, T3 makes the same dose of GH produce less IGF-1 in vivo than usual. It is more effective to reduce the dose of GH to an individual's appropriate level.
When T3 dose is greater than 50 mcg / day, the effectiveness of inactivation of GH is particularly significant. If it is present at a dose of 25 mcg / day, it does not seem to be obvious.


abstract
T3 is a very effective compound to help losing weight, but excessive use can cause serious side effects. If you're careful, it's a compound that's easy to recycle. Because T3 has limited stability, it is best it’s best sourced from quality pharmaceutical products, with a second choice being Third World generics or relatively-fresh powder which has been carefully measured. Liquid products can lose potency rapidly and therefore are not preferred.